Management of In-Transit Malignant Melanoma
نویسندگان
چکیده
In-transit melanoma is a unique pattern of recurrence that occurs in up to ten percent of pa‐ tients with melanoma. In-transit disease denotes multifocal tumor deposits occurring be‐ tween the site of the primary lesion and its regional draining lymph node basin [1, 2]. It is an independent adverse prognostic factor and is frequently associated with distant metastasis. This pattern of recurrence represents a challenging management problem, but provides unique treatment modalities as well. In addition, studying in-transit melanoma has the po‐ tential to shed additional light on melanoma biology. The goal of this chapter is to discuss the presentation, underlying disease biology, and various current treatment strategies for this unique pattern of recurrence in melanoma.
منابع مشابه
Diagnosis and Management of a Malignant Dermal Melanoma in a Donkey (Equus asinus)
Case Description- A 2-yr-old intact male donkey (Equus asinus) was presented to Hospital of Veterinary Medicine, Mansoura University with subcutaneous masses under the tail. Clinical Findings- Physical examination revealed the presence of 2 separate 5x10 and 5x8-cm-diameter, round and firm subcutaneous masses. Treatment and Outcome<...
متن کاملBone marrow and cervical lymph nodes metastases as prodromal manifestations of malignant melanoma in a child
Malignant melanoma in children is rare. It can arise from congenital melanocytic nevi. In pediatric patients, diagnosis of melanoma is difficult and challenging because the physicians have a low index of suspicion. Marrow metastasis in malignant melanoma especially in children is extremely uncommon. Here, the authors reported a 5 year old girl who was presented with a 4 month history of pelvic ...
متن کاملMalignant Melanoma in Khouzestan: Study of 62 cases
Background: Malignant melanoma is the leading cause of death among skin cancers in western countries. However, the incidence, histologic subtypes, and tumor behaviors are quite different in Asians and western populations. Objective: This study was designed to survey the clinicopathological aspects of malignant melanoma among Khouzestan people. Patients and Methods: In a retrospective stud...
متن کاملPrimary Malignant Melanoma of the Gastrointestinal Tract: Report of Two Cases
Although gastrointestinal involvement by metastatic malignant melanoma is common but primary gastrointestinal (GI) melanoma has been reported in rare cases. In this study we report two cases of primary gastrointestinal malignant melanoma that one of them is a known case of neurofibromatosis type 1(NF1). Both cases showed no evidence of any lesions in skin and eye. Malignant melanoma of GI tract...
متن کاملPigmented Bowens disease mimicking malignant Melanoma: A case report
Pigmented Bowens disease is an in situ squamous cell carcinoma, which is seldom reported in white patients. Herein we report a 20-year-old woman with type III skin, who had this lesion on the fourth finger of her right hand, similar to superficial malignant melanoma, clinically. Although dermoscopic evaluation could be helpful, correct diagnosis of non-melanotic origin is done by histological e...
متن کامل